Bioinformatics Tools

GitBook allows you to organize your book into chapters, each chapter is stored in a separate file like this one.

Samtools

Samtools is a suite of programs for analyzing large scale sequencing data. It contains three separate packages samtools, BCFtools, and HTSlib.

Samtools documentation can be found here.

Examples:

Selected regions of bam file and output to another bam file.

samtools view aln.sorted.bam chr2:20,100,000-20,200,000 -b > out.bam

Select regions from fastq file

samtools faidx teo20.fa 1:1-10000

Kmer Approaches

Pan Kmer reference, see Dolle et al., BioRxiv

Imputation

Rapid genotype imputation from seq without ref panels. Davies, et al., 2016.

Convert using Assembly Converter

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